Multi-organ Linkage Pathophysiology and Therapy for NAFLD and NASH

by Tomoo Yamazaki, Takefumi Kimura, Gabriel Rufino Estrela

NAFLD and NASH refer to the hepatic phenotype of metabolic syndromes strongly associated with obesity, diabetes, and dyslipidemia. NAFLD and NASH have complex pathogenesis modulated not only by the liver but also by muscle, adipose tissue, pancreas, gut microbiome, and immune and central nervous systems. This complex pathology, coupled with insulin resistance, lipid and bile acid changes, and congenital genetic predisposition, induces liver injury due to oxidative stress, endoplasmic reticulum s

ISBN: 9782832553534

126 pages

Published: 2024-08-22

Publisher: Frontiers Media SA

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